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Efficacy Results from Controlled Clinical Studies The effect on one of the major end points, maintenance of erections after penetration, is shown in Figure 6, for the pooled results of 5 fixed-dose, dose-response studies of greater than one month duration, showing response according to baseline function. In these studies, involving about patients, analyses of patient diaries showed no effect of VIAGRA on rates of attempted intercourse about 2 per week , but there was clear treatment-related improvement in sexual function: per patient weekly success rates averaged 1. Pharmacokinetic data from patients in clinical trials showed no effect on sildenafil pharmacokinetics of CYP2C9 inhibitors such as tolbutamide, warfarin , CYP2D6 inhibitors such as selective serotonin reuptake inhibitors, tricyclic antidepressants , thiazide and related diuretics, ACE inhibitors, and calcium channel blockers. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. The titration studies, in which most patients received mg, showed similar results.Sildenafil (Viagra) is a medicine used to treat erectile dysfunction (ED, also called impotence). Sildenafil works by helping to relax the blood vessels in the penis, allowing more blood to flow in and cause an erection. You should take sildenafil about an hour before planned sexual activity, so it has time to work. Viagra (sildenafil) is a prescription drug that’s used to treat erectile dysfunction (ED). The drug comes as a tablet you’ll take by swallowing. It’s usually taken as needed about 1 hour. Drug Images What is Viagra? If you have erectile dysfunction (ED), your doctor may recommend that you take Viagra. It’s a prescription drug that’s used in adult .